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Low INR to Minimize Bleeding With Mechanical Valves Trial

NCT03636295

This study evaluates the use of a lower INR target (1.5 to 2.5) in patients with a mechanical bileaflet heart valve in the aortic position. This study will inform physicians about whether a lower INR target will decrease the risk of bleeding or increase the risk of blood clot formation and stroke. These results have the potential to reduce the burden of bleeding in patients with a mechanical heart valve who require lifelong warfarin (Coumadin) treatment.

Bleeding Post-mechanical Valve ReplacementThromboembolism Post-mechanical Valve Replacement

Population Health Research Institute2,625 participantsStarted Sep 2019

Genk, Limburg, Belgium • Ostend, West-Vlaanderen, Belgium • Keerbergen, Belgium +32 more locations

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Low INR to Minimize Bleeding With Mechanical Valves Trial

Low INR to Minimize Bleeding With Mechanical Valves Trial