Heart Disease Clinical Trials in New York

Showing 201-220 of 585 trials

SGLT2-Inhibitors for Sleep Apnea in Heart Failure

NCT04640493

Heart Failure is a disease involving many different aspects of the human body, including changes in metabolism, the way the body produces and uses energy. Research shows that patients with heart failure often have a sleep disorder called sleep disordered breathing (SDB). It has been shown that SDB is associated with poor outcomes in heart failure patients, but the exact reason is unknown. It is likely that SDB leads to changes in metabolism and hormone status in the body, which is especially dangerous for heart failure patients. There is currently no treatment for SDB in heart failure patients. Recently, with Sodium glucose co-transporter 2 (SGLT2)-Inhibitors a new drug class has been approved for the treatment of advanced heart failure. This drug has effects on the metabolism in heart failure patients, among several other effects. This research project has the aim to investigate if SGLT2 inhibitors can help in the treatment of SDB, as many mechanisms of the drug overlap with the mechanisms how SDB develops. The drug has been approved by the FDA for the treatment of heart failure. The investigators want to study the effect of the drug on SDB by using a home sleep test called Watchpat, which has been approved to diagnose SDB.

Heart FailureSleep Disordered Breathing

Columbia UniversityStarted Dec 2023

New York, New York, United States

COMPLETED< 1 mile

Investigation to Optimize Hemodynamic Management of Left Ventricular Assist Devices Using the CardioMEMS™

NCT03247829

This observational post market study is intended to characterize hemodynamic-guided management of patients with an existing left ventricular assist device (LVAD) to protocol specified target ranges and its impact on functional status, quality of life, and readmissions

Heart Failure

Abbott Medical Devices101 participantsStarted Aug 2017

La Jolla, California, United States • Los Angeles, California, United States • Los Angeles, California, United States +20 more locations

SGLT2-Inhibitors for Sleep Apnea in Heart Failure

Investigation to Optimize Hemodynamic Management of Left Ventricular Assist Devices Using the CardioMEMS™

Heart Disease Trials in Other Cities

A Study to Evaluate the Effect of Testosterone Replacement Therapy (TRT) on the Incidence of Major Adverse Cardiovascular Events (MACE) and Efficacy Measures in Hypogonadal Men

Change of Fructose to Fat in South Asians

Myocardial Injury and Major Adverse Outcomes in Patients With COVID-19

REDUCE LAP-HFREF TRIAL

Evaluation of Home-based Sensor System to Detect Health Decompensation in Elderly Patients With History of CHF

A Study to EXhibit Percutaneous Coronary Artery Dilatation With Non-Slip Element Balloon

Congenital Heart Disease: Impact on Learning and Development in Down Syndrome (CHILD-DS)

Effect of Evolocumab on Coronary Plaque Characteristics

Early Revascularization in Stable Ischemic Heart Disease Using P.E.T. Imaging

Patient Centered Machine Learning Model for Bleeding and Ischemic Risk

Multiple Cardiac Sensors for the Management of Heart Failure

Safe Surveillance of PCI Under Mechanical Circulatory Support With the Saranas Early Bird Bleed Monitoring System

ELUCIDATE FFRct Study

A Clinical Trial to Confirm Safety & Effectiveness of the SYNERGY 4.50 mm and 5.00 mm Stent for Treatment of Atherosclerotic Lesion(s)

Use of Oxandrolone to Promote Growth in Infants With HLHS

Screening for Asymptomatic Coronary Artery Disease in Kidney Transplant Candidates

Cardionomic STOP-ADHF Study

Association of Endothelial Function and Clinical Outcomes in Subjects Admitted to Chest Pain Unit

Other Conditions in New York