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Clinical Trials Colorectal CancerTennessee

Colorectal Cancer Clinical Trials in Tennessee

Find 454 clinical trials for colorectal cancer near Tennessee. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Tennessee

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 121-140 of 454 trials

RecruitingA Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 ExpressionThe goal of this study is to test autologous logic-gated Tmod™ CAR T-cell products in subjects with solid tumors including colorectal cancer (CRC), pancreatic cancer (PANC)…NCT06051695·Gilbert, Arizona and 11 others Active not recruitingA Study of E7386 in Combination With Other Anticancer Drug(s) in Participants With Solid TumorThe primary objective of this study is to assess the safety and tolerability and to determine the recommended Phase 2 dose (RP2D) of E7386 in combination with other anticancer…NCT04008797·Little Rock, Arkansas and 105 others

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Data from ClinicalTrials.govTerms

CompletedLYT-200 Alone and in Combination With Chemotherapy or Tislelizumab in Patients With Locally Advanced or Metastatic Solid TumorsA Phase 1/2 Open-label, Multi-center Study of the Safety, Pharmacokinetics, and Anti-tumor Activity of LYT-200 Alone and in Combination with Chemotherapy or Tislelizumab in…NCT04666688·Los Angeles, California and 11 others

Active not recruitingA Study of JZP815 Oral Capsules in Adult Participants With Advanced or Metastatic Solid Tumors Harboring Mitogen Activated Protein Kinase (MAPK) Pathway Alterations to Investigate the Safety, Dosing, and Antitumor Activity of JZP815This phase 1 study will investigate the safety, dosing, and initial antitumor activity of JZP815 in participants with advanced or metastatic solid tumors harboring alterations in…NCT05557045·Los Angeles, California and 14 others

CompletedPhase I Study of KRN330 Monoclonal Antibody in Patients With Colorectal CancerThe primary objective of this study is to assess the safety and tolerability of KRN330 in patients with relapsed or refractory advanced or metastatic colorectal cancer.NCT00575562·Nashville, Tennessee and 1 other

CompletedStudy of Irinotecan and Cetuximab Versus Irinotecan as Second-Line Treatment in Patients With Metastatic, EGFR-Positive Colorectal CancerThe purpose of this study is to determine whether overall survival is prolonged in subjects with metastatic, epidermal growth factor receptor (EGFR)-positive colorectal cancer…NCT00063141·Tucson, Arizona and 187 others

CompletedPhase I/Ib Study of NIS793 in Combination With PDR001 in Patients With Advanced Malignancies.To characterize the safety and tolerability of NIS793 as single agent and in combination with PDR001 and to identify recommended doses for future studies.NCT02947165·Nashville, Tennessee and 11 others

Active not recruitingA Study of Botensilimab and Balstilimab for the Treatment of Colorectal CancerThis is an open-label, Phase 2, multicenter study to evaluate the efficacy, safety, tolerability, and pharmacokinetic profiles of botensilimab as monotherapy and in combination…NCT05608044·Scottsdale, Arizona and 64 others

RecruitingA Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal CancerThe purpose of this study is to evaluate the safety and efficacy of pumitamig in combination with chemotherapy versus bevacizumab in combination with chemotherapy in participants…NCT07221357·Tucson, Arizona and 285 others

RecruitingA Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid TumorsThe main purpose of this study is to evaluate the safety and preliminary efficacy of CHS-114 in combination with toripalimab and/or other standard of care (SOC) compound(s) in…NCT06657144·Tucson, Arizona and 29 others

Active not recruitingStudy of Onvansertib in Combination With FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab Versus FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab for First-Line Treatment of Metastatic Colorectal Cancer in Adult Participants With a KRAS or NRAS MutationThe purpose of this study is to assess 2 different doses of onvansertib to select the lowest dose that is maximally effective, and to assess the safety, efficacy…NCT06106308·Phoenix, Arizona and 40 others

CompletedMulti-marker Stool Test for Detection of Colorectal Neoplasia: Marker Panel Selection and Technical Development StudiesThe objective of this study is to confirm the sensitivity of a stool DNA test for detection of colorectal cancer and pre-cancer.NCT01260168·Birmingham, Alabama and 20 others

CompletedA Study of Xeloda (Capecitabine) in Patients With Advanced and/or Metastatic Colorectal CancerThis study will assess the efficacy and safety of continuous oral Xeloda administration in combination with intravenous irinotecan as a first-line treatment in patients with…NCT00048126·Hoover, Alabama and 9 others

TerminatedStudy of Ruxolitinib in Colorectal Cancer PatientsThe purpose of this study was to determine if ruxolitinib, in combination with regorafenib, is safe and effective in the treatment of metastatic colorectal cancer.NCT02119676·Chandler, Arizona and 85 others

CompletedS0030: Capecitabine in Treating Older Patients W/Metastatic or Recurrent Colorectal Cancer That Cannot Be Surgically RemovedRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00049335·Mobile, Alabama and 89 others

CompletedAn Exploratory Pharmacogenomic Study of Monotherapy Erbitux in Subjects With Metastic Colorectal CancerThe purpose of this study is to predict response to Erbitux as a single agent in patients with metastatic colon cancerNCT00207155·Duarte, California and 13 others

Active not recruitingTTX-080 HLA-G Antagonist in Subjects With Advanced CancersTTX-080-001 is a Phase 1, open label, dose escalation and dose expansion clinical study to determine the safety, tolerability, and recommended Phase 2 dose of TTX-080 monotherapy…NCT04485013·Tucson, Arizona and 40 others

CompletedEffect of Panitumumab on the Pharmacokinetics of IrinotecanThe primary objective of this study is to determine if panitumumab affects the pharmacokinetic (PK) profile of irinotecan.NCT00563316·Billings, Montana and 11 others

CompletedDNA Evaluation of Fragments for Early Interception - Lung Cancer Training Study (DELFI-L101 Study)The primary objective of this study, DELFI-L101, is to train and test classifiers for lung cancer detection using the DELFI assay and other biomarker and clinical features.NCT04825834·Homewood, Alabama and 56 others

CompletedFirst Line Metastatic Colorectal Cancer Therapy in Combination With FOLFOXThe purpose of this study is to see if Cediranib in combination with FOLFOX is effective in treating metastatic colorectal cancer and to see how it compares with Avastin…NCT00384176·Anniston, Alabama and 279 others

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Other Conditions in Tennessee

Breast Cancer Lung Cancer Prostate Cancer Melanoma Leukemia Lymphoma