ALS Clinical Trials in Chicago

Showing 21-40 of 79 trials

Long-Term Evaluation of BIIB067 (Tofersen)

NCT03070119

The primary objective of the study is to evaluate the long-term safety and tolerability of BIIB067 (tofersen) in participants with amyotrophic lateral sclerosis (ALS) and confirmed superoxide dismutase 1 (SOD1) mutation. The secondary objectives are to evaluate the pharmacokinetic (PK), pharmacodynamic (PD), biomarker effects, and efficacy of BIIB067 administered to participants with ALS and a confirmed SOD1 mutation.

ALS Caused by Superoxide Dismutase 1 (SOD1) Mutation

Biogen139 participantsStarted Mar 2017

Phoenix, Arizona, United States • La Jolla, California, United States • San Francisco, California, United States +27 more locations

Active Not RecruitingNA2.2 miles

Impact of Sensory Electrical Stimulation on Sensation and Tremor

NCT06428526

The purpose of this study is to understand the acute, short-term and long-term impact of transcutaneous and/or percutaneous electrical stimulation with afferent-specific electrical stimulation (asES) on proprioception and fine motor control in the upper extremity. For this purpose, the researchers will use transcutaneous and/or percutaneous asES, high-density electromyography (HD-EMG), arm kinematic measurements, and standardized clinical assessments. This study will be conducted in healthy able-bodied individuals and patients with essential tremor (ET).

Essential TremorHealthy Individuals

Shirley Ryan AbilityLab40 participantsStarted Jan 2025

Chicago, Illinois, United States

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Long-Term Evaluation of BIIB067 (Tofersen)

Impact of Sensory Electrical Stimulation on Sensation and Tremor

ALS Trials in Other Cities

Efficacy and Safety of MSC-NTF (NurOwn) in Participants With Early Symptomatic ALS and Moderate Disease Presentation in ALS (ENDURANCE STUDY)

A Second Intermediate-Size Expanded Access Protocol (EAP) for Pridopidine in People With Amyotrophic Lateral Sclerosis (Pridopidine EAP 2)

Intermediate Expanded Access Protocol CNMAu8.EAP04

A Study to Evaluate the Efficacy and Safety of Reldesemtiv in Patients With Amyotrophic Lateral Sclerosis (ALS)

Pain Injection Versus Epidural Anesthesia for Hip Surgery in Pediatric Patients With Cerebral Palsy

A Pilot Trial of Lithium in Subjects With Progressive Supranuclear Palsy or Corticobasal Degeneration

Stepping to Understand Lower Limb Impairments in Bilateral Cerebral Palsy

Telehealth Implementation of Brain-Computer Interface

Ready, Set, Go! A Physical Fitness Intervention for Children With Mobility Challenges

Study to Assess the Effects of PTC857 Treatment in Participants With Amyotrophic Lateral Sclerosis ALS

MERIDIAN: A Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Adults With Amyotrophic Lateral Sclerosis (ALS)

A Compassionate Use Protocol of AMX0035 for Treatment of Patients With Amyotrophic Lateral Sclerosis (ALS)

Safety Study of XT-150 in Participants With ALS

Prospective Database Registry Study of Scoliosis in Children With Cerebral Palsy

Phase 2, Randomized, Double Blind, Placebo Controlled Multicenter Study of Autologous MSC-NTF Cells in Patients With ALS

Expanded Access Protocol: Repeated Administration of Nurown® (Autologous MSC-NTF Cells) for the Treatment of ALS

Arimoclomol in Amyotropic Lateral Sclerosis

The Impact of Dosing Parameters on Motor Skill Acquisition and Retention in Bilateral Cerebral Palsy (BCP)

Other Conditions in Chicago