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Intravenous Atropine in Reducing Reperfusion Arrhythmias, Conduction Abnormalities and Hypotension in Inferior ST-elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention | Clinical Trials | Clareo Health

COMPLETEDPHASE4

Intravenous Atropine in Reducing Reperfusion Arrhythmias, Conduction Abnormalities and Hypotension in Inferior ST-elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

NCT07268586•Ain Shams University

View on ClinicalTrials.gov

Summary

People with acute inferior wall myocardial infarction will be given an intravenous drug called atropine that increases the heart rate to check if it prevents heart rhythm disturbances during performing coronary intervention

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Acute inferior ST elevation myocardial infarction

Exclusion Criteria

•Execution of rescur percutaneous coronary intervention after thrombolysis
•Mechanical complications or no reflow or spontaneous reperfusion.
•Prior implantation of permanent or temporary pacemakers
•History of bradycardia, hypotension or ventricular tachycardia with a definitive cause (unrelated to the disease under study)
•Prior coronary artery bypass graft surgery
•Atropine contraindications Unwillingness to participate in the

Locations (1)

Ain Shams University

Cairo, Abbasia, Egypt

Key Dates

Start Date

August 1, 2025

Primary Completion Date

February 28, 2026

Completion Date

February 28, 2026

Last Updated

March 10, 2026

Enrollment

158

ACTUAL participants

Conditions

Myocardial Infarction

Interventions

Intravenous atropine immediately before wire crossing during primary percutaneous coronary intervention

DRUG

Intravenous normal saline as placebo immediately before wire crossing during primary percutaneous coronary intervention

DRUG

Fast Discharge After Acute Myocardial Infarction Discharge MI

NCT06744322

Acute Myocardial Infarction (AMI)

View study

RECRUITINGPHASE2

Stratified Medicine of Eplerenone in Acute Myocardial Infarction or Injury and no Obstructive Coronary Arteries.

NCT05198791

Myocardial Infarction, AcuteMyocardial Infarction With Nonobstructive Coronary Arteries+1 more

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 10, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Intravenous Atropine in Reducing Reperfusion Arrhythmias, Conduction Abnormalities and Hypotension in Inferior ST-elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

Inclusion Criteria

Exclusion Criteria

Fast Discharge After Acute Myocardial Infarction Discharge MI

Stratified Medicine of Eplerenone in Acute Myocardial Infarction or Injury and no Obstructive Coronary Arteries.

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