Loading clinical trials...

Problem-Solving Skills Training for Parents of Children Undergoing Hematopoietic Stem Cell Transplantation: A Feasibility Study | Clinical Trials | Clareo Health

COMPLETEDNA

Problem-Solving Skills Training for Parents of Children Undergoing Hematopoietic Stem Cell Transplantation: A Feasibility Study

NCT07219524•Children's Hospital Los Angeles

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to test the feasibility and acceptability of the Bright IDEAS problem-solving skills training (PSST) intervention for parents of children undergoing hematopoietic stem cell transplantation (HSCT). The main question aims to answer: * Determine the feasibility and acceptability of a multimodal PSST intervention for English and Spanish-speaking parents of children and adolescents undergoing autologous and allogeneic HSCT using a randomized controlled trial design and mixed methods approach to evaluation * To evaluate the effectiveness of a PSST intervention on PSS acquisition and psychological distress compared to a control group of parents receiving non-directive psychosocial care (n=25). * To explore the effect of the parent PSST on child quality of life (QoL) and self-reported symptoms, mediated by parent psychological distress If there is a comparison group: Researchers will compare PSST intervention usual or standard psychosocial care. Participants will complete 6-8 sessions of intervention. All participants will complete surveys.

Eligibility

Age

0 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Children
•Male and females of any race or ethnicity, ages 0 to 21 years
•Allogeneic or autologous HSCT planned with reduced intensity or myeloablative conditioning
•One parent or primary caregiver per child
•Able to speak, read, and write English or Spanish, and give informed consent

Exclusion Criteria

•Concurrent enrollment on a research study testing psychoeducational interventions for parents and/or patients
•Parent
•Child or adolescent refusal to participate
•Parent age less than 18 years.

Locations (1)

Children's Hospital Los Angeles

Los Angeles, California, United States

Key Dates

Start Date

November 11, 2020

Primary Completion Date

May 23, 2023

Completion Date

May 23, 2023

Last Updated

October 23, 2025

Enrollment

ACTUAL participants

Conditions

Stem Cell Transplantation

Interventions

Bright Ideas Problem-Solving Skills Training

BEHAVIORAL

Ruxolitinib-Decitabine Intensified Conditioning Regimen for AML: A Randomized Trial

NCT07101588

Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)

View study

RECRUITINGPHASE1/PHASE2

The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation

NCT05436418

Peripheral Blood Stem Cell TransplantationHematopoietic Stem Cell Transplantation

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: October 23, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Problem-Solving Skills Training for Parents of Children Undergoing Hematopoietic Stem Cell Transplantation: A Feasibility Study

Inclusion Criteria

Exclusion Criteria

Ruxolitinib-Decitabine Intensified Conditioning Regimen for AML: A Randomized Trial

The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation

Early Detection of Infectious and Noninfectious Lung Diseases Following Allogeneic Hematopoietic Stem Cell Transplantation

Nutritional Status of Patients After Hematopoietic Stem Cell Transplantation

Prevention of Graft Rejection in Hematopoietic Stem Cell Transplant (HSCT) Recipients

Employment Support After Hematopoietic Stem Cell Transplantation