Dosimetric Differences and Clinical Significance Analysis Between Body Gamma Knife and VMAT Radiotherapy for Primary Liver Cance

Inclusion Criteria

• •Aged 18-75 years.
• •Clinically or pathologically confirmed primary liver cancer; unsuitable for or - refusing surgery, with single tumor diameter ≤5 cm and ≤5 nodules.
• •ECOG PS score 0-1.
• •Liver function: Child-Pugh grade A or B.
• •Prothrombin time (PT) \< 4 seconds above the normal control range.
• •No hepatic encephalopathy or moderate to large ascites.
• •Renal and cardiopulmonary function basically normal.
• •Gastroscopy findings: no severe esophageal varices or active peptic ulcer.
• •Hemoglobin ≥90 g/L, WBC ≥3.0×10⁹/L, neutrophil ≥1.5×10⁹/L, platelet ≥40×10⁹/L.
• •No obvious cachexia; life expectancy \> 3 months.
• •Not pregnant; no HIV or syphilis infection.
• •Able to understand the study and sign informed consent.