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AI-Guided Left Bundle Branch Area Pacing | Clinical Trials | Clareo Health

RECRUITINGNA

AI-Guided Left Bundle Branch Area Pacing

A Pilot Study Assessing Outcomes Of Artificial Intelligence-Guided Left Bundle Branch Area Pacing For Cardiac Resynchronization In Heart Failure

NCT07206602•Mayo Clinic

View on ClinicalTrials.gov

Summary

The purpose of this study is to compare the effectiveness of AI-guided LBBAP versus conventional LBBAP (not AI-guided) in improving CRT response rates and clinical outcomes.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Age: 18 years or older.
•Left Ventricular Ejection Fraction (LVEF): \<50% within 6 months prior to enrollment.
•QRS Duration: Resting QRS duration ≥ 130 ms on ECG OR anticipated right ventricular pacing \> 40% OR device in place with right ventricular pacing \> 40% within 6 months prior to enrollment.
•Medical Therapy: Optimized on guideline-directed medical therapy for heart failure.
•AI-ECG probability of low LVEF: \>0.5

Exclusion Criteria

•Age less than 18 years old
•Inability to follow-up
•Pregnancy

Locations (1)

Mayo Clinic in Rochester

Rochester, Minnesota, United States

Key Dates

Start Date

January 23, 2026

Primary Completion Date

November 1, 2027

Completion Date

November 1, 2027

Last Updated

February 18, 2026

Enrollment

224

ESTIMATED participants

Conditions

Heart Failure

Interventions

AI-assisted Left Bundle Branch Area Pacing

DEVICE

Left Bundle Branch Area Pacing

PROCEDURE

Contacts

Joseph Abdel Messih

CONTACT

507-422-3967 mansour.joseph@mayo.edu

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 18, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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AI-Guided Left Bundle Branch Area Pacing

Inclusion Criteria

Exclusion Criteria

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