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Oral Versus Intravenous Acetaminophen in Lumbar Spine Surgery | Clinical Trials | Clareo Health

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Oral Versus Intravenous Acetaminophen in Lumbar Spine Surgery

A Randomized, Double-Blind, Placebo-Controlled Trial Comparing 48-Hour Post-Operative Administration of Oral Versus Intravenous Acetaminophen in Patients Undergoing Lumbar Spine Fusion Surgery

NCT07203079•Stanford University

View on ClinicalTrials.gov

Summary

The goal of this study is to compare whether oral or intravenous acetaminophen works better for pain control in patients undergoing lumbar spine fusion surgery

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Plan for open lumbar laminectomy and fusion surgery (1-3 levels)
•Able to provide written informed consent
•Must be able to swallow pills

Exclusion Criteria

•Medical contraindications to acetaminophen
•Emergency surgery
•Chronic pain unrelated to surgery
•Pregnancy

Locations (1)

Stanford University

Stanford, California, United States

Key Dates

Start Date

January 1, 2026

Primary Completion Date

October 1, 2026

Completion Date

January 1, 2027

Last Updated

October 8, 2025

Enrollment

180

ESTIMATED participants

Conditions

Postoperative Pain

Interventions

Acetaminophen Oral Tablet

DRUG

placebo oral tablet

DRUG

Acetaminophen infusion

DRUG

Placebo infusion

DRUG

QIPB in Inguinal Hernia

NCT06862609

Postoperative Pain

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RECRUITING

Ultrasound-Guided Transversus Abdominis Plane Block Versus Epidural Block for Umbilical Hernia Analgesia

NCT07327463

Umbilical HerniaPostoperative Pain Management

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RECRUITINGNA

SPS Block vs. Surgical Intercostal Block for Chronic Pain After Thoracoscopic Surgery

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: October 8, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Oral Versus Intravenous Acetaminophen in Lumbar Spine Surgery

Inclusion Criteria

Exclusion Criteria

QIPB in Inguinal Hernia

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SPS Block vs. Surgical Intercostal Block for Chronic Pain After Thoracoscopic Surgery

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