Treatment of Peritrapezial Osteoarthritis With Isolated Trapeziometacarpal Arthroplasty in 300 Patients

Treatment of Peri-trapezial Osteoarthritis With Isolated Trapeziometacarpal Arthroplasty

NCT07169474•Clinique Saint Jean, France

Summary

The aim of this clinical trial is to assess the functional outcomes of isolated trapeziometacarpal joint arthroplasty in adult patients requiring surgical management of trapeziometacarpal osteoarthritis, with or without associated symptoms. The primary endpoint is the evolution of the Quick DASH functional score between inclusion (preoperative) and one year postoperatively. The study design is a follow-up study of a multicenter cohort.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Patient requiring surgical management
•Clinical and radiographic diagnosis of peri-trapezial osteoarthritis in the 1 or 2 joints:
•TM osteoarthritis: glickel sign + grinding test STT osteoarthritis: pain on wrist mobilization in flexion-extension and prono-supination
•TM (Eaton-Littler stages II to III) and STT (Crosby stages II and III) radiographic osteoarthritis
•Persistent pain and functional limitations despite conservative treatment for at least 6 months (combining intermittent immobilization of wrist and thumb + joint infiltration of the 2 joints)
•Ability to understand and sign the informed consent form.

Exclusion Criteria

•History of surgery on the affected thumb.
•Systemic inflammatory diseases (e.g. rheumatoid arthritis).
•Active infection or history of joint infection of the upper limb.
•Inability to participate in post-operative follow-up.

Locations (1)

Clinique St jean sud de france

Montpellier, France

Key Dates

Start Date

September 9, 2025

Primary Completion Date

July 30, 2027

Completion Date

July 30, 2027

Last Updated

November 25, 2025

Enrollment

300

ESTIMATED participants

Conditions

Trapeziometacarpal Osteoarthritis

Interventions

Isolated trapeziometacarpal arthroplasty with double mobility

PROCEDURE

Contacts

Cecile Spirito

CONTACT

0033467413399 cecile.spirito@capsante.fr

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: November 25, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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