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This clinical trial aims to determine whether beta-band transcranial alternating current stimulation (tACS) can improve impulse inhibition in adolescents with non-suicidal self-injury (NSSI) and to evaluate its safety. The primary questions it seeks to answer are: * Can beta-band tACS significantly reduce the frequency of self-injury and scores on impulsivity scales in adolescents with NSSI? * What discomfort or medical issues may participants experience during tACS intervention? Researchers will compare beta-band tACS with sham stimulation (a procedure that mimics the real stimulation without delivering effective current) to verify its efficacy. Participants will: * Receive two sessions of either tACS or sham stimulation daily, spaced 4 hours apart, for 7 consecutive days (14 sessions in total). * Undergo scale assessments, behavioral tasks, and eye-tracking tests before and after the intervention. * Record any self-injury episodes and adverse reactions, with continuous monitoring and psychological support provided by a professional team.
Age
12 - 22 years
Sex
ALL
Healthy Volunteers
No
School of Mental Health and Psychological Sciences, Anhui Medical University
Hefei, Anhui, China
Start Date
March 1, 2025
Primary Completion Date
May 31, 2026
Completion Date
May 31, 2026
Last Updated
September 3, 2025
60
ESTIMATED participants
Beta-frequency transcranial alternating current stimulation
DEVICE
sham beta-frequency transcranial alternating current stimulation
DEVICE
Lead Sponsor
Anhui Medical University
NCT06793397
NCT07051200
Data Source & Attribution
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