Effect of Platelet-Rich Plasma on Graft Uptake and Postoperative Outcomes in Full-Thickness Skin Grafting of Face and Neck

Exclusion Criteria

• •Patients with systemic conditions known to impair wound healing, including uncontrolled diabetes mellitus (HbA1c \>8%), severe peripheral vascular disease, collagen vascular disorders, or immunodeficiency.
• •Patients with hematological disorders affecting platelet count or function, including thrombocytopenia (platelet count \<150,000/µL), coagulopathies, or platelet dysfunction syndromes.
• •Patients on systemic anticoagulation therapy (e.g., warfarin, DOACs) or corticosteroids within the last 4 weeks.
• •Presence of active local infection or purulent discharge at the recipient or donor site at the time of surgery.
• •History of previous radiation to the grafted site or underlying malignancy with ongoing treatment.