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Patient-reported Outcomes (PRO) and Treatment Outcomes of Chinese Patients With MSS-type Advanced Colorectal Cancer Who Received the Zidovudine Combination Regimen in the Real World: A Prospective, Multicenter, Observational Study Protocol
The Chidamide + sintilimab ± bevacizumab regimen has become a post-treatment option for clinicians and patients after being included in the guidelines. The CAPability-01 study is a phase II RCT, with a limited number of enrolled subjects. Further observation of the safety and clinical real-world application status of the sidibemab combination regimen is needed in a larger sample size prospective observational cohort study. The primary endpoint of this study is the safety events of the sidibemab combination regimen.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
West China Hospital Sichuan University
Chengdu, Sichuan, China
Start Date
July 10, 2025
Primary Completion Date
July 30, 2026
Completion Date
July 30, 2027
Last Updated
August 6, 2025
300
ESTIMATED participants
Lead Sponsor
West China Hospital
NCT06696768
NCT04704661
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