Loading clinical trials...
Loading clinical trials...
*Effect of Prophylactic Common Bile Duct Stenting Versus Non Stenting on Recurrence of Common Bile Duct Stones in Patients Awaiting Cholecystectomy*
Primary objective: Compare recurrence rates of CBD stones in stented versus non-stented patients. Secondary objectives: Identify predictors of stone recurrence. Assess the incidence and risk factors for post-ERCP complications. Evaluate time to recurrence and rate of hospital readmissions. Explore impact on quality of life and ease of subsequent cholecystectomy.
Choledocholithiasis, the presence of stones in the common bile duct (CBD), occurs in 10-20% of patients with symptomatic gallstones and can lead to severe complications such as obstructive jaundice, cholangitis, and pancreatitis Endoscopic retrograde cholangiopancreatography (\*\*ERCP\*\*) with stone extraction is the gold standard treatment, achieving \>90% success rates in ductal clearance. Despite successful initial clearance, CBD stone recurrence remains a significant issue, with reported rates ranging from 4% to 24% . To reduce recurrence, prophylactic biliary stenting has been proposed, particularly in high-risk patients (e.g., large or multiple stones, dilated CBD, periampullary diverticulum) However, its routine use remains controversial due to conflicting evidence on efficacy, stent-related complications (e.g., migration, occlusion, cholangitis), and increased healthcare costs.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Assiut university
Asyut, Egypt
Start Date
August 1, 2025
Primary Completion Date
September 1, 2026
Completion Date
December 1, 2026
Last Updated
August 7, 2025
88
ESTIMATED participants
CBD stent either a 7-Fr and 7 cm or a 10-Fr and 7-cm OR double-pigtail stent
DEVICE
biliary stent
DEVICE
Huda Mokhtar Huda Mokhtar, Assistant lecturer, master degree
CONTACT
0201154664323hudamokhtar2571994@aun.edu.egLead Sponsor
Assiut University
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.
View ClinicalTrials.gov Terms and Conditions