Romiplostim N01 for Chemotherapy-induced Thrombocytopenia

Exclusion Criteria

• •Those with uncontrollable primary diseases of important organs, such as extensive metastasis of malignant tumors, liver failure, heart failure, kidney failure and other diseases；
• •Patients with poor compliance;
• •Positive serology for HIV, hepatitis B virus (HBV), hepatitis C virus (HCV), and/or hepatitis D virus (HDV), Syphilis; Positive for Epstein-Barr Virus DNA, Cytomegalovirus DNA;
• •Accompanied by extensive and severe bleeding, such as hemoptysis, upper gastrointestinal bleeding, intracranial hemorrhage, etc.
• •There is currently a heart disease requiring treatment or a poorly controlled hypertension judged by the investigator；
• •Patients with thrombotic diseases such as pulmonary embolism, thrombosis, and atherosclerosis；
• •Those who have received allogeneic stem cell transplantation or organ transplantation in the past；
• •Patients with mental disorders who cannot normally obtain informed consent and undergo trials and follow-up；
• •Patients whose toxic symptoms caused by treatment before participating in the trial have not disappeared；
• •Other serious diseases that may restrict participants from participating in this trial (such as diabetes; severe heart failure; myocardial obstruction or unstable arrhythmia or unstable angina in the past 6 months; gastric ulcers; mobility Autoimmune diseases, etc.)；
• •Patients with sepsis or patients with other irregular bleeding；
• •Patients taking antiplatelet drugs at the same time；
• •Pregnant women, suspected pregnancy (a positive pregnancy test for human chorionic gonadotropin in urine at screening) and breastfeeding patients； Pre-existing cardiac disease, including congestive heart failure of New York Heart Association \[NYHA\] Grade III/IV, arrhythmia requiring treatment or myocardial infarction within the last 6 months. No arrhythmia known to increase the risk of thrombotic events (e.g. atrial fibrillation), or patients with a QT \>450msec or QTc \> 480 for patients with a Bundle Branch Block;
• •Researchers believe that patients should not participate in the test of any other condition.