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Longitudinal Characterization of Inner Retina Health in Low Vision Retinitis Pigmentosa Patients to Optimize Retinal Ganglion Cell-based Optogenetic Vision Restoration Therapy
The aim of this study is an explorative prospective observation of retinal ganglion cell degeneration and/or inner retina degeneration in Retinitis pigmentosa patients. The rate and patterns of progression will be correlated to the outer retina layers as well as clinical and genetic data of patients. Secondary goal is to determine potential parameters for optogenetic treatment eligibility.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
EKFZ Else Kroener Fresenius Center for Optogenetic Therapies, University Medical Center Goettingen
Göttingen, Germany
Start Date
March 1, 2025
Primary Completion Date
March 1, 2030
Completion Date
April 1, 2030
Last Updated
July 9, 2025
130
ESTIMATED participants
imaging
DIAGNOSTIC_TEST
Lead Sponsor
University Medical Center Goettingen
NCT05926583
NCT07174726
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.
View ClinicalTrials.gov Terms and ConditionsNCT07292987