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COMPLETED

Risk Factors Affecting Mortality in Perforated Peptic Ulcer

Risk Factors Affecting Morbidity and Mortality in Perforated Peptic Ulcer

NCT07050199•Maharajgunj Medical Campus

Summary

Perforation is one of the most severe and life-threatening complications of peptic ulcer disease. This study aims to evaluate the risk factors associated with postoperative morbidity and mortality in patients undergoing surgery for peptic ulcer perforation, with a focus on the timing of presentation, demographic variables, surgical delay, and their association with postoperative outcomes.

Eligibility

Age

15 - 75 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Patients with peptic ulcer perforation aged\> 15 years and \<75 years.
•Patients with duodenal or gastric perforation of peptic ulcer origin.
•Patients who underwent simple closure with omental patch as a standard operative procedure.

Exclusion Criteria

•Patients treated with conservative management.
•Patients with perforation of peptic ulcer origin at the jejunum, ileum adjacent to Meckel's diverticulum.
•Patients presenting with recurrent perforation or stomal ulcer perforation.

Locations (1)

National Medical College and Teaching Hospital

Birgunj, Nepal

Key Dates

Start Date

April 1, 2022

Primary Completion Date

March 30, 2023

Completion Date

March 30, 2023

Last Updated

July 3, 2025

Enrollment

ACTUAL participants

Conditions

Peptic Ulcers

Interventions

Emergency laparotomy

PROCEDURE

Hemospray Versus the Combined Conventional Technique for Endoscopic Hemostasis of Bleeding Peptic Ulcers : A Pilot Study

NCT02088385

Bleeding Peptic Ulcers

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WITHDRAWNPHASE4

Comparison of Intravenous Omeprazole to Ranitidine on Recurrent Bleeding After Endoscopic Treatment of Bleeding Ulcer

NCT00247130

Peptic Ulcers

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UNKNOWNPHASE3

Oral Versus IV Proton Pump Inhibitor in High-risk Bleeding Peptic Ulcers After Endoscopic Hemostasis

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: July 3, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

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