Loading clinical trials...

Effectiveness of HabitWorks and Symptom Tracking for Anxiety and Depression | Clinical Trials | Clareo Health

COMPLETEDNA

Effectiveness of HabitWorks and Symptom Tracking for Anxiety and Depression

NCT07025486•Mclean Hospital

Summary

Our objective is to conduct a randomized controlled trial (RCT) that compares two digital interventions - Symptom Tracking and the HabitWorks app - in a sample of adults endorsing symptoms of anxiety or depression. We hope to obtain pilot data to support a fully powered RCT to test moderators: 1. Target engagement (improvement in interpretation bias) 2. Feasibility and acceptability of Symptom Tracking and HabitWorks and procedures for a general community sample 3. Symptom and functioning measures

Detailed Description

HabitWorks is a personalized, transdiagnostic, smartphone-delivered interpretation bias intervention. Our pilot studies of HabitWorks revealed good acceptability, feasibility, and target engagement in a variety of populations (Beard, Ramadurai, et al., 2021; Beard, Beckham, et al., 2021). Our next step is to test effectiveness for anxiety and depression symptoms in a larger, community sample. Results will provide pilot data to support an R01 effectiveness trial. We will randomize adults with anxiety or depression to HabitWorks or a credible control arm and examine effects on interpretation bias, symptoms, and functioning.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•1. Age ≥ 18 at the time of consent (19 in Nebraska, 21 in Puerto Rico based on age of consent)
•2. Current US resident
•3. Total score ≥ 3 on the Patient Health Questionnaire-2 (Kroenke et al., 2003) or Generalized Anxiety Disorder-2 (Spitzer et al., 2006), indicating at least mild depression and/or anxiety symptoms
•4. 24-hour access to an iPhone smartphone
•5. ability to understand English

Exclusion Criteria

•1. No current psychiatric symptoms that would prevent informed consent, understanding of research procedures, or ability to complete the study (e.g., active symptoms of psychosis, mania)
•2. No medical symptoms that would prevent informed consent, understanding of research procedures, or ability to complete the study (e.g., physical disability)

Locations (1)

McLean Hospital

Belmont, Massachusetts, United States

Key Dates

Start Date

March 13, 2024

Primary Completion Date

April 4, 2025

Completion Date

April 4, 2025

Last Updated

June 17, 2025

Enrollment

340

ACTUAL participants

Conditions

AnxietyDepression, Anxiety

Interventions

HabitWorks

BEHAVIORAL

Symptom TRacking

BEHAVIORAL

Readiness and Progress in Emotion Regulation Therapy

NCT07478393

RuminationWorry+4 more

View study

RECRUITINGNA

ACTsocially: The (Dis)Similarities of ACT for Changing Internalizing and Externalizing Symptomatology in Adolescence

NCT07456631

Social Anxiety Disorder (SAD)Oppositional Defiant Disorder

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: June 17, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Effectiveness of HabitWorks and Symptom Tracking for Anxiety and Depression

Inclusion Criteria

Exclusion Criteria

Readiness and Progress in Emotion Regulation Therapy

ACTsocially: The (Dis)Similarities of ACT for Changing Internalizing and Externalizing Symptomatology in Adolescence

"Erectile Function After PCI in MI and Non-MI Patients"

In Vivo Exposure vs. Videochat-Based Vicarious Exposure

Effects of Darkness Retreat: a Pilot Study

Transcranial Alternating Current Stimulation for Generalized Anxiety Disorder and Insomnia: An Open-Label Pilot Study