Predicting Mortality in Patients With Return of Spontaneous Circulation After Cardiac Arrest

This is a prospective observational study conducted in the intensive care unit (ICU) of Gazi Yaşargil Training and Research Hospital, Turkey. The study aims to identify independent predictors of in-hospital mortality in patients who achieve return of spontaneous circulation (ROSC) after cardiac arrest. Adult patients (age ≥ 18 years) who were resuscitated after cardiac arrest and admitted to the ICU are consecutively included. Data are collected prospectively on admission and within the first 24 hours, including demographic characteristics, cause and type of arrest, time to ROSC, initial rhythm, hemodynamic parameters, neurological status, lactate, pH, base excess, biomarkers, and therapeutic interventions. Primary outcome is 30-day in-hospital mortality. Secondary outcomes include neurological outcome at discharge and ICU length of stay. Patients are followed up until hospital discharge or death. The data will be analyzed using multivariate logistic regression to identify independent risk factors for mortality. The study was approved by the institutional ethics committee, and no intervention beyond routine care is performed. Results are expected to improve clinical prognostication and guide decision-making for patients with ROSC after cardiac arrest.