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Clinical Evaluation of the Efficacy of a Food Supplement in Relieving Premenstrual Syndrome (PMS) Symptoms: a Randomized, Double-blind, Parallel-group, Placebo-controlled Study
The aim of this clinical trial, funded by Activ'Inside, is to evaluate the efficacy of a food supplement in relieving Premenstrual Syndrome (PMS) Symptoms. The study will be performed on 110 healthy women who experience mild/moderate Premenstrual Syndrome (PMS) symptoms, under the supervision of a board-certified Gynecologist. Half of the subjects will assume the active product and half of the subjects will assume a placebo (a product without active ingredients). Specific assessments will be carried out before and after 1, 2 and 3 menstrual cycles of product intake. Also, the possible occurrence of adverse events will be recorded.
Age
18 - 45 years
Sex
FEMALE
Healthy Volunteers
Yes
Nutratech S.r.l. - Via Francesco Todaro 20/22
Rende, Cosenza, Italy
Complife Italia S.r.l. - Via Mortara 171
Ferrara, Ferrare, Italy
Complife Italia S.r.l. - Via Signorelli 159,
Garbagnate Milanese, Milan, Italy
Complife Italia S.r.l. - Piazzale Siena 11
Milan, Milan, Italy
Complife Italia SRL - Corso San Maurizio 25
Biella, Pavia, Italy
Complife Italia SRL- Via Monsignor Angelini 21
San Martino Siccomario, Pavia, Italy
Start Date
September 1, 2025
Primary Completion Date
May 1, 2026
Completion Date
May 1, 2026
Last Updated
January 15, 2026
110
ESTIMATED participants
plant extract
DIETARY_SUPPLEMENT
Placebo
DIETARY_SUPPLEMENT
Lead Sponsor
Activ'inside
NCT06724419
NCT07078708
NCT02402049
Data Source & Attribution
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