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To date, more than 300 patients have been treated with Glofitamab in the Expanded Access Programme (EAP) in France. In this study, it is proposed to perform a retrospective analysis of some of these patients. The aim is to describe the efficacy and safety of Glofitamab in the largest reported real-world cohort, with an expected median follow-up of more than 9 months. Particular focus will be given to the relapsed or refractory chimeric antigen receptors-T (CAR-T) population to confirm the response rates (CRR: 35-39%) of Glofitamab in this population and to assess the optimal timing of therapy initiation \[8, 15\].
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
CH Victor Dupouy
Argenteuil, France
CH d'Avignon - Hôpital Henri Dufaut
Avignon, France
CH de la Côte Basque
Bayonne, France
CHRU Besançon - Hôpital Minjoz
Besançon, France
Hopital D'Instruction Des Armees Percy
Clamart, France
Hopital Henri Mondor
Créteil, France
CHU de Dijon - Hôpital le Bocage
Dijon, France
CH de Dunkerque
Dunkirk, France
CHU de Grenoble - Hôpital Albert Michallon
La Tronche, France
Hôpital de Libourne
Libourne, France
Start Date
December 1, 2025
Primary Completion Date
March 30, 2026
Completion Date
July 30, 2026
Last Updated
January 14, 2026
250
ESTIMATED participants
Glofitamab
DRUG
Lead Sponsor
The Lymphoma Academic Research Organisation
NCT05139017
NCT06026319
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
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