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Efficacy of Warm Compress Therapy in Enhancing Tear Film Quality and Reducing Postoperative DES | Clinical Trials | Clareo Health

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Efficacy of Warm Compress Therapy in Enhancing Tear Film Quality and Reducing Postoperative DES

Efficacy of Warm Compress Therapy in Enhancing Tear Film Quality and Reducing Postoperative Dry Eye Syndrome After Cataract Surgery: A Randomized Controlled Trial

NCT06914232•Superior University

View on ClinicalTrials.gov

Summary

Dry eye disease (DED) is a multifactorial condition often exacerbated by cataract surgery, leading to discomfort and visual disturbances. Meibomian gland dysfunction (MGD), a key cause of DED, contributes to tear film instability, which can be managed with warm compress therapy.

Detailed Description

This study aims to evaluate the effectiveness of perioperative warm compress therapy (TPT) in improving tear film stability and reducing dry eye symptoms following cataract surgery. This randomized controlled trial (RCT) will involve 54 patients with estimated attrition rate 60 participants aged 50-70 with moderate to severe dry eye symptoms and tear film instability, as indicated by high Ocular Surface Disease Index (OSDI) scores. Participants will be randomly assigned to either an intervention group, receiving warm compress therapy before and after surgery, or a control group receiving standard dry eye treatments for 6 weeks.

Eligibility

Age

50 - 70 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Patients aged 30 to 70 years
•Patients scheduled for cataract surgery (both unilateral and bilateral).
•Patients with preoperative moderate to severe dry eye symptoms, which will be assessed using the Ocular Surface Disease Index (OSDI).

Exclusion Criteria

•Patients with OSDI, indicating severe dry eye disease which suggests severe dry eye disease. These patients might require more intensive treatments beyond Warm Compress therapy.
•Patients with systemic diseases (e.g., rheumatoid arthritis, lupus) that affect tear production or who are using medications that severely reduce tear production (e.g., chronic use of antihistamines or systemic corticosteroids).
•Patients with significant pre-existing corneal pathology (e.g., corneal dystrophies, corneal scars) that could affect the results of cataract surgery or thermal pulsation therapy.
•Patients with active ocular infections (e.g., conjunctivitis, keratitis) or inflammation at the time of screening or surgery.
•Patients with a history of previous ocular surgeries (excluding cataract surgery) in the study eye, such as refractive surgery (LASIK, PRK) or corneal transplants.
•Patients with a known allergy or contraindication to Warm Compress therapy or its components.

Locations (1)

Hakeem mahmood trust hospital address alam chowk mean baipas

Gujranwala, Punjab Province, Pakistan

Key Dates

Start Date

March 20, 2025

Primary Completion Date

June 20, 2025

Completion Date

February 20, 2026

Last Updated

April 6, 2025

Enrollment

ACTUAL participants

Conditions

Dry Eye Syndrome

Interventions

Warm Compress

COMBINATION_PRODUCT

Standard Care

DIAGNOSTIC_TEST

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RECRUITINGNA

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: April 6, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Efficacy of Warm Compress Therapy in Enhancing Tear Film Quality and Reducing Postoperative DES

Inclusion Criteria

Exclusion Criteria

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