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Effectiveness of Recruitment, Retention Strategies, and Data Collection Quality: A Feasibility Study in Combat Athletes With Mild Traumatic Brain Injury
The use of Hyberbaric Oxygen Therapy (HBOT) would be a new treatment plan rather than conventional rest. If effective, this new use technology would add to the clinical treatment among mild traumatic brain injury (mTBI) patients. The use of a point of care Glial Fibrillary Acidic Protein (GFAP) biomarker would aid in clinical decision making to create a new care plan of return to sport among unarmed combat athletes who suffer from mTBI. The innovation would be a new treatment and diagnosis strategy that will protect these athletes from serious long-term sequelae. There are no published randomized controlled studies using HBOT to treat concussed athletes within one week of injury. There are no published studies using GFAP levels to predict post concussive symptoms (PCS).
Age
18 - No limit years
Sex
MALE
Healthy Volunteers
Yes
Marshfield Clinic
Marshfield, Wisconsin, United States
Start Date
August 7, 2025
Primary Completion Date
September 1, 2026
Completion Date
December 31, 2026
Last Updated
August 13, 2025
10
ESTIMATED participants
Hyberbaric Oxygen Therapy
DEVICE
Lead Sponsor
Michael Harl
NCT04521881
NCT07455136
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT06725108