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This study aims to assess the feasibility and effectiveness of laparoscopic toupet fundoplication (LTF) for treating gastroesophageal reflux disease (GERD) symptoms and disease-specific Quality of Life (QoL).
Heartburn, regurgitation, dysphagia, and chest pain are regarded as common esophageal symptoms of gastroesophageal reflux disease (GERD). On the other hand, there are very few reports of laryngopharyngeal reflux (LPR), which is associated with persistent upper airway contact, acidic and non-acidic reflux, and aerosol that results in posterior laryngitis, edema, and glottis erythema. Proton-pump inhibitor (PPI) therapy, Laparoscopic Nissen Fundoplication (LNF), and Laparoscopic Toupet Fundoplication (LTF) have been proven to be effective for the treatment of GERD. However, the therapeutic management of patients with hiatal hernia is debated and treatment remains empirical. Previous studies on PPI therapy and LNF had been published with promising but controversial results. Therefore, the role of LTF is even less explored and evidence is scarce
Age
18 - 70 years
Sex
ALL
Healthy Volunteers
No
Minia University
Minya, Egypt
Start Date
August 25, 2024
Primary Completion Date
December 1, 2025
Completion Date
December 1, 2025
Last Updated
March 19, 2025
100
ESTIMATED participants
Laparoscopic toupet fundoplication
PROCEDURE
Lead Sponsor
Minia University
Data Source & Attribution
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