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Prospective, Randomized, Controlled Trial of Preoperative Use of Saxenda (Liraglutide) Additionally to Common Dietological Measures as Opposed to Dietological Measures Alone
The aim of the study is to investigate the effects of preoperative Saxenda (liraglutide). There are two groups, one group receives Saxena in addition to dietary measures when first seeking the operation, one group only diet. The investigator is researching how much additional preoperative weight loss is possible with the drug admitted preoperatively.
The aim of the study is to investigate the effects of preoperative Saxenda (liraglutide). There are two groups, one group receives Saxena in addition to dietary measures, one group only diet. Each group will have a waiting period of 6 months until the operation will be done. The investigator wants to elaborate how much additional preoperative weight loss is possible with the drug. The greater the preoperative weight loss, the lower the risk of the operation. After one year, the investigator will also check whether the weight loss has been maintained and whether the preoperative Saxenda continues to lose even more weight after the operation. All patients looking for bariatric surgery with health insurance via Österreichische Gesundheitsklasse and BMI\>35kg/m2 will be asked to take part in this study. Patients with previous bariatric surgeries or contraindications against liraglutide will be excluded from this study.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Start Date
May 1, 2025
Primary Completion Date
February 1, 2027
Completion Date
February 1, 2028
Last Updated
March 21, 2025
72
ESTIMATED participants
Liraglutide daily (0.6-3.0mg, highest tolerable dose) additional to dietological measures and lifestyle optimization suggestions
DRUG
Dietologic measures and lifestyle optimization for weight loss
BEHAVIORAL
Moritz Felsenreich, Ap.Prof.Priv.-Doz.DDr.
CONTACT
0043014040056210moritz.felsenreich@meduniwien.ac.atLead Sponsor
Medical University of Vienna
NCT06822387
NCT05982847
Data Source & Attribution
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