Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Beni-Suef University
the inhaled nitroglycerin is expected to make vasodilatation of the pulmonary arteries and arterioles which are constricted in late stages of COBD leading to ventilation/perfusion mismatching and further aggravating COPD. it will also help in delivering better antibiotic concentrations to the alveoli which help in better control of infection.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Adult patient's ≥ 18 years old COPD exacerbation with respiratory failure and Echo evidenced presence of pulmonary hypertension (defined as mean pulmonary artery pressure \> 20 mmHg)
You may not be if
Profound left ventricular failure, as the decrease in pulmonary vascular resistance results in an increase in left ventricular preload. This may worsen cardiogenic pulmonary edema.
Pregnant female patients
Patient with hypersensitivity to nitroglycerin
Clareo Health | "The Effect of Inhaled Nitroglycerin for COPD Patients