Loading clinical trials...

Garlic Oil As Root Filling Material in Primary Molars | Clinical Trials | Clareo Health

NOT_YET_RECRUITINGNA

Garlic Oil As Root Filling Material in Primary Molars

Evaluation of Allium Sativum As Root Filling Material for Primary Molars Indicated for Non Vital Pulp Therapy: Randomized Clinical Trials

NCT06755502•Cairo University

View on ClinicalTrials.gov

Summary

The goal of this study is to test garlic oil mixed with zinc oxide as a potential root canal filling material of primary molars in children aged from four to eight years. the study hypothesized that garlic oil mixed with zinc oxide would be the same as the gold standard filling material (metapex). The group receiving the garlic oil with zinc oxide as root canal filling material will be compared with other similar group receiving metapex as root canal filling material in terms of clinical and radio-graphic success, and working time.

Detailed Description

This study is a randomized clinical trial (RCT), that aims compare the clinical and radio-graphic success of garlic oil mixed with zinc oxide, used as root canal filling material in primary molars in children aged from four to eight years, with the conventional root filling material, which is metapex.

Eligibility

Age

4 - 8 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•1. Primary second molars which are diagnosed with irreversible pulpitis, or pulp necrosis.
•2. Presence of sinus tract.
•3. Periapical bone swelling.
•4. Continuous bleeding after amputation of the coronal pulp tissue.
•5. No pulp tissue remains when the pulp chamber is accessed.
•6. Pus discharges from the canal.
•7. Radiographically, only primary molars with at least two-thirds of the root length.
•8. Presence of inter-radicular or periapical radiolucency.

Exclusion Criteria

•1\. A tooth with internal root resorption will not be included. 2. Excessive tooth mobility beyond healing. 3. Carious perforation in the pulpal flour. 4. A tooth with a pathological lesion extending to the successor's tooth germ. 5. Non-restorable primary molars.
•\-

Key Dates

Start Date

August 8, 2025

Primary Completion Date

October 8, 2026

Completion Date

November 8, 2026

Last Updated

March 20, 2025

Enrollment

ESTIMATED participants

Conditions

Irreversible Pulpitis (toothache)

Interventions

Garlic oil

COMBINATION_PRODUCT

Calcium Hydroxide, Iodoform, paste

DRUG

Contacts

Mennat Allah A. A. Elkareem

CONTACT

+20 1026022605 mennatallah.ashraf@dentistry.cu.edu.eg

Evaluation of the Success Rate of Pulpotomy Versus to Root Canal Therapy in Management of Mature First Permanent Molars With Irreversible Pulpitis

NCT07046533

Irreversible Pulpitis (Toothache)Dental Caries (Diagnosis)

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 20, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions