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Impact Of Metformin In Rectal Cancer Patients | Clinical Trials | Clareo Health

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COMPLETEDPhase 2/3NCT06728982

Impact Of Metformin In Rectal Cancer Patients

Design: Prospective, randomized controlled clinical trial Setting: at Minia University Hospital and Minia Oncology Institute. Condition: Colorectal cancer. To be eligible for participation, patients ...

Lead sponsor: Minia University•2 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Minia University

Age

18 - 65 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•1. Histologically confirmed diagnosis of rectal adenocarcinoma.
•2. Age starting from 18 and older.
•3. Eastern Cooperative Oncology Group (ECOG) performance status of 0-2.
•4. Adequate organ function (renal, hepatic, and hematological)
•5. Signed informed consent.

Exclusion Criteria

•1. Metastatic disease.
•2. Contraindications to metformin.
•3. Significant comorbidities or medical conditions that may interfere with study participation. (D.M, PCO,..)
•4. eGFR less than 30 mL/min.
•5. Pregnant or breastfeeding women.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: August 1, 2025Terms

Trial snapshot

StatusCOMPLETED

PhasePHASE2/PHASE3

Enrollment85

Start dateMay 2024

Last updatedAug 1, 2025

Condition

Rectal Cancer Patients

Locations shown

Minia Oncology Center

Minya, Egypt

Minia University Hospital

Minya, Egypt

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: August 1, 2025Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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