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High Potassium Diet with Spices and Herbs As Salt Substitute for Lowering Blood Pressure in Older Adults: Study Protocol | Clinical Trials | Clareo Health

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High Potassium Diet with Spices and Herbs As Salt Substitute for Lowering Blood Pressure in Older Adults: Study Protocol

High Potassium Diet Rich in Spices and Herbs-Salt Substitution (HPSH-SS) for Blood Pressure Reduction in Older Adults: Protocol for Diet Concept and Randomized Controlled Trial

NCT06683430•Universitas Airlangga

View on ClinicalTrials.gov

Summary

This clinical trial aims to evaluate the High Potassium Diet Rich in Spices and Herbs-Salt Substitution (HPSH-SS) for reducing blood pressure in older adults. The study has two phases: the first focuses on developing a high-potassium, low-sodium diet, while the second involves a 14-day randomized controlled trial. Participants are divided into two groups: the intervention group (IG) receives an 1800 kcal daily diet with 3500 mg potassium and 1500 mg sodium, while the control group (CG) receives a diet with 1500 mg potassium and 2000 mg sodium. Key outcomes include changes in blood pressure, serum potassium, aldosterone, nitric oxide, and oxidative stress markers. The results could provide new dietary strategies for managing blood pressure in the elderly.

Eligibility

Age

60 - No limit years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•older adults aged ≥60 years residing in the nursing
•active and not bedridden
•without infectious disease, taste disorders, or dementia
•have blood pressure measurements indicating a systolic blood pressure (SBP) ≥130 mmHg and/or diastolic blood pressure (DBP) ≥85 mmHg

Exclusion Criteria

•individuals with impaired kidney function (creatinine serum levels \>1.2 mmol/L)
•uncontrolled diabetes mellitus (fasting blood sugar \>126 mg/dL)
•obesity (BMI ≥30 kg/m2 )
•active smokers
•have memory impairment and depressive conditions
•participants declining continued participation, requiring intensive hospital care, or experiencing persistent vomiting and diarrhea were excluded from the intervention.

Locations (1)

government institutional setting in Surabaya, Indonesia, namely Griya Wreda Surabaya nursing home.

Surabaya, Jawa Timur, Angola

Key Dates

Start Date

May 11, 2022

Primary Completion Date

June 30, 2023

Completion Date

February 9, 2024

Last Updated

November 12, 2024

Enrollment

ACTUAL participants

Conditions

HypertensionOlder Adults Institutionalized in Residential Homes

Interventions

High Potassium, Low Sodium Diet

DIETARY_SUPPLEMENT

Standard Diet

DIETARY_SUPPLEMENT

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RECRUITINGPHASE2

A Study to Learn About the Study Medicine (Called PF-07868489) in People With Pulmonary Arterial Hypertension Who Have Previously Participated in a Clinical Study With PF-07868489

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Pulmonary Hypertension

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: November 12, 2024Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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High Potassium Diet with Spices and Herbs As Salt Substitute for Lowering Blood Pressure in Older Adults: Study Protocol

Inclusion Criteria

Exclusion Criteria

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