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Endoscopic Gastroenterostomy Versus Surgical Gastrojejunostomy for Treatment of Malignant Gastric Outlet Obstruction: a Randomized Controlled Trial
Recent comparative data suggest that EUS gastroenterostomy offers more durable patency than enteral stents for treatment of malignant GOO, leading some endoscopists to suggest that EUS gastroenterostomy should be the preferred endoscopic treatment approach. EUS gastroenterostomy and surgical gastrojejunostomy have been compared in retrospective cohort analysis, suggesting a high technical success rate a shorter hospital length of stay for the endoscopic approach \[4\]. Comparison of these techniques has not been reported in controlled prospective fashion. A prospective trial is necessary in order to define the optimal interventional management option for treatment of malignant GOO in the context of the contemporary and rapidly evolved range of available endoscopic and surgical treatment options.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Vanderbilt University Medical Center
Nashville, Tennessee, United States
Start Date
August 1, 2025
Primary Completion Date
January 1, 2027
Completion Date
January 1, 2027
Last Updated
August 26, 2025
34
ESTIMATED participants
EUS Gastrojejunostomy
PROCEDURE
Surgical Gastrojejunostomy
PROCEDURE
Gastric Outlet Obstruction Scoring System (GOOSS)
OTHER
Lead Sponsor
Vanderbilt University Medical Center
NCT05986890
NCT06128018
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.
View ClinicalTrials.gov Terms and ConditionsNCT03223831