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The Impact of Targeted Temperature Management Duration on Thrombin Function in Cardiac Arrest Patients (ITTC Trial): A Single-Center, Prospective, Randomized Controlled Trial
This study will be a single-center, prospective, randomized controlled trial with an estimated sample size of 64 patients. Eligible patients will be randomly assigned in a 1:1 ratio to receive TTM for either 24 hours or 72 hours. The primary outcome measure will be the changes in thrombin function indices at various time points during TTM treatment in both groups. The secondary endpoints of the study include additional coagulation function indicators, the incidence of bleeding-related events between the two groups, the amount of blood products used, the incidence of thrombotic events, and the CPC scores at 28 days and 6 months for both groups.
Age
18 - 80 years
Sex
ALL
Healthy Volunteers
No
Beijing chao-yang Hospital, Capital Medical University
Beijing, Beijing Municipality, China
Start Date
December 1, 2024
Primary Completion Date
December 31, 2025
Completion Date
December 31, 2025
Last Updated
April 11, 2025
64
ESTIMATED participants
Target Temperature Management Treatment
PROCEDURE
Lead Sponsor
Tang Ziren
NCT07438938
NCT07363772
Data Source & Attribution
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