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The Desensitising Effect of Nanosilver Fluoride in Molar-Incisor Hypomineralisation | Clinical Trials | Clareo Health

COMPLETEDPHASE2/PHASE3

The Desensitising Effect of Nanosilver Fluoride in Molar-Incisor Hypomineralisation

The Desensitising Effect of Nanosilver Fluoride Compared to Low-Level Laser Therapy in Molar-Incisor Hypomineralisation: A Randomised Controlled Clinical Trial

NCT06348849•Alexandria University

View on ClinicalTrials.gov

Summary

The aim of the current study is to assess the desensitising effect of nanosilver fluoride on first permanent molars (FPMs) in patients with MIH in comparison to low-level laser therapy.

Eligibility

Age

7 - 10 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•The presence of at least one hypersensitive first permanent molar in MIH patient (using the Schiff Cold Air Sensitivity Scale (SCASS)).
•Completion of an informed consent to participate in the study.

Exclusion Criteria

•Hypomineralised molars resulting from other medical conditions, such as enamel malformations associated with syndromes, dental fluorosis, enamel hypoplasia, amelogenesis imperfecta, and dental caries.
•The presence of active tooth decay or defective restorations in the tooth under examination which can confound the aetiology of hypersensitivity with pulpitis.
•The presence of pulpal symptoms.
•Having undergone any professional desensitising treatment in the previous 6 months.
•Having used a desensitising paste other than habitual toothpaste in the previous 3 months.
•Use of anti-inflammatory drugs or analgesics at the time of recruitment.
•Allergy or sensitivity to silver or any of the materials included in the study.

Locations (1)

Faculty of Dentistry, Alexandria University

Alexandria, Egypt

Key Dates

Start Date

April 1, 2024

Primary Completion Date

June 1, 2024

Completion Date

August 1, 2024

Last Updated

January 30, 2025

Enrollment

120

ACTUAL participants

Conditions

Molar Incisor HypomineralizationHypersensitivity

Interventions

Low-level laser therapy

DEVICE

Nanosilver fluoride

DRUG

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RECRUITINGNA

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 30, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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The Desensitising Effect of Nanosilver Fluoride in Molar-Incisor Hypomineralisation

Inclusion Criteria

Exclusion Criteria

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