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Postoperative and Long-term Outcomes of Transanal Tran-section and Single-stapled Anastomosis (TTSS) in Rectal Can-cer Patients: a Multicentric International IDEAL Stage 2b Prospective Parallel Cohort Study
The Transanal Transection and Single-Stapled anastomosis (TTSS) technique may be a valid alternative to traditional double-stapled anastomosis for low rectal cancer surgery. This study aims to compare the postoperative and functional outcomes of patients receiving TTSS and traditional double-stapled anastomosis.
The Transanal Transection and Single-Stapled anastomosis (TTSS) technique has become a valid alternative to the standard double-stapled anastomosis approach in the surgical treatment of low rectal cancer. Recent evidence showed a significantly reduced number of anastomotic leaks in patients undergoing TTSS compared with patients receiving double-stapled anastomosis, suggesting that TTSS may be technically feasible and may provide a surgical advantage over the traditional double-stapled technique. However, these studies were severely limited by their single-center and retrospective nature. This study aims to confirm the retrospective findings by extending the data collection to additional countries and provide prospective data collection.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
IRCCS Humanitas Research Hospital
Rozzano, MI, Italy
Start Date
March 26, 2024
Primary Completion Date
May 31, 2027
Completion Date
December 31, 2027
Last Updated
June 27, 2024
472
ESTIMATED participants
Transanal Transection and Single-Stapled anastomosis (TTSS)
PROCEDURE
Double-stapled Total Mesorectal Excision (TME)
PROCEDURE
Lead Sponsor
Istituto Clinico Humanitas
Data Source & Attribution
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