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To compare whether AK104 combined with GP or PFLL can improve survival benefit, safety and tolerability in nasopharyngeal carcinoma patients who have failed first-line treatment; To compare the survival benefits of GP or GFLL treatment in nasopharyngeal carcinoma patients who had failed first-line therapy; To compare the survival benefits of GP or GFLL combined with AK104 in patients with nasopharyngeal carcinoma who had failed first-line therapy.
Age
18 - 75 years
Sex
ALL
Healthy Volunteers
No
Department of Radiation Oncology, Sun Yat-Sen University Cancer Center
Guangzhou, Guangdong, China
Start Date
February 1, 2024
Primary Completion Date
February 1, 2026
Completion Date
February 1, 2029
Last Updated
February 5, 2024
300
ESTIMATED participants
GP/PFLL+AK104
DRUG
GP/PFLL+placebo
DRUG
Lead Sponsor
Sun Yat-sen University
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