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Use of D-dimers in the Emergency Department to Identify Adult Patients at Very Low Risk of Mortality for Fast-track Treatment - a Randomized Controlled Study
Emergency departments (ED) internationally are treating an increasing number of patients. Most require hospital services but some could be better cared for on alternative pathways. D-dimer has some unique properties. It is non-specific and is elevated in many acute condi- tions; but conversely remains normal in the absence of significant disease. Previous studies have shown that having a normal D-dimer on arrival to the emergency department is associated with a very low risk of 30-day all-cause mortality. The investigators propose a multicenter randomized controlled trial using D-dimer to identify patients at low risk and test if providing this information will change time to discharge disposition by the treating physician.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Esbjerg Hospital
Esbjerg, Syd, Denmark
Odense University Hospital
Odense, Syd, Denmark
Start Date
January 22, 2024
Primary Completion Date
July 1, 2025
Completion Date
August 1, 2025
Last Updated
April 9, 2025
1,538
ESTIMATED participants
D-dimer
DIAGNOSTIC_TEST
Lead Sponsor
Odense University Hospital
Collaborators
NCT06668636
NCT06345352
Data Source & Attribution
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