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Department of Orthopedic Oncology, The First Affiliated Hospital of Sun Yat-sen University
Retrospective analysis of specific characteristics of complications and long-term oncological and function outcomes in lower-limb osteosarcoma pediatric patients.
Clinical and functional outcomes were compared based on age groups, surgical methods, type of prosthesis, and primary tumor location. Patients were divided into the Low-age group (≤10 years old) and the High-age group (\>10 years old). Overall Survival rate (OS), Progression-Free Survival rate (PFS), and prosthesis survival rate were assessed using Kaplan-Meier curves, and non-parametric survival analysis (log-rank test) was used for comparison. The incidence of complications, local relapse rate (LRR), metastasis rate, final limb-salvage and amputation rate, and Musculoskeletal Tumor Society (MSTS) score of different independent groups were further evaluated using χ2 test or Fisher's exact test, and t-test was employed to evaluate the measurement data.
Age
4 - 14 years
Sex
ALL
Healthy Volunteers
No
Changye Zou
Guangzhou, Guangdong, China
Start Date
January 1, 2000
Primary Completion Date
November 23, 2023
Completion Date
November 23, 2023
Last Updated
December 8, 2023
345
ACTUAL participants
Retrospective analysis
OTHER
Lead Sponsor
Changye Zou
NCT07479732
NCT07478380
Data Source & Attribution
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