Lead Sponsor

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Age

12 - No limit years

Sex

MALE

Healthy Volunteers

No

•Patients with XLRS with cystoid fluid collections involving the fovea confirmed on SD- OCT
•are willing to undergo ophthalmic examinations at seven separate occasions;
•have no visual dysfunction that is also significantly associated with other ocular diseases besides XLRS (e.g., glaucoma, perforating trauma);
•have no known (non-)ocular disease/disorder which may influence the results of the measurements.

•Severe hepatic impairment
•Severe renal insufficiency
•Sodium and Potassium Depletion
•Addison's disease
•Hyperchloremic Acidosis
•Cor pulmonale
•Chronic non-congestive angle-closure glaucoma
•Usage of acetazolamide
•Known allergy or intolerance for ocular anesthetic eye drops oxybuprocaine 0.4% or mydriatics tropicamide 0.5% and/or phenylephrine 5%;