Patient with an acute, isolated, severe brain injury (SAH, TBI, ICH)
Glasgow coma score \<8
Monitored using ICP device
Presenting an episode of intracranial hypertension requiring osmotherapy. ( defined as increase in ICP 25 mmHg which persisted for more than 5 min in the absence of noxious stimulations)
Informed Consent as documented by signature
You may not be if
Pregnant woman
Bilateral fixed dilatated pupils
Initial hypernatremia (\>155 mmol/l)
Penetrating head injury
Active participation to another trial (Clin B, C)
Clareo Health | Sodium Lactate Versus Hypertonic Saline Solution in the Treatment of Intracranial Hypertensive Episodes in Severe Brain Injured Patients