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Performance of New Diagnostic Methods in Older Adults With Pneumonia | Clinical Trials | Clareo Health

RECRUITING

Performance of New Diagnostic Methods in Older Adults With Pneumonia

Establishing and Implementing Pneumonia Diagnosis in ED Older Adults: A Mixed Methods Approach

NCT06092008•Ohio State University

Summary

Create a clinical diagnostic pathway for older ED adults with pneumonia and its subgroups (bacterial, viral, and co-infection) and determine whether novel biomarkers improve diagnostic accuracy. The investigators will conduct a prospective observational trial of 250 ED patients ≥65 years old with suspected pneumonia. The investigators will perform analyses overall and by subgroups, seeking common models to ease adoption.

Eligibility

Age

65 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•\- Adults aged 65 and older presenting to the ED with suspected pneumonia defined as (1) either a physician order for CXR OR CT OR a chief complaint consistent with dyspnea; AND (2) physician suspicion of pneumonia prior to ED testing (score of 2-5 on Likert scale)

Exclusion Criteria

•inability to obtain consent from the patient or an LAR
•active cancer
•organ transplant
•immunosuppression
•trauma activation
•suicidal ideation
•incarceration
•antibiotics in the last 14 days
•a separate episode of lower respiratory illness in the last 30 days

Locations (1)

The Ohio State University

Columbus, Ohio, United States

Key Dates

Start Date

December 2, 2022

Primary Completion Date

September 30, 2026

Completion Date

June 30, 2027

Last Updated

February 6, 2026

Enrollment

250

ESTIMATED participants

Conditions

Pneumonia

Contacts

Michael Hill, RN

CONTACT

614-293-6185 michael.hill@osumc.edu

Effect of Acetylcysteine Inhalation on Incidence and Time to Develop Ventilator Associated Pneumonia in Critically Ill Mechanically Ventilated Patients

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Ventilation Acquired Pneumonia

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Driving Pressure During Surgeries With High Risk for Postoperative Pulmonary Complications

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 6, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Performance of New Diagnostic Methods in Older Adults With Pneumonia

Inclusion Criteria

Exclusion Criteria

Effect of Acetylcysteine Inhalation on Incidence and Time to Develop Ventilator Associated Pneumonia in Critically Ill Mechanically Ventilated Patients

Driving Pressure During Surgeries With High Risk for Postoperative Pulmonary Complications

Health Systems and Policy Contexts of Medical Oxygen

High PEEP in Noninvasive Ventilation Patients With Pneumonia or ARDS

Evaluating the Safety and Performance of the MiniLung Petite Kit in Neonatal and Pediatric Patients With Acute Respiratory and Cardiac Failure

Diagnostic and Prognostic Value of Reticulated Platelet Fraction in Ventilator-Associated Pneumonia (REPLAY-VAP)