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Comparison of the Effects of Dexamethasone and magnesıum Sulphate Used as Adjuvant in Infraclavicular Brachial Plexus Nerve Block.
The aim of this prospective clinical study is to compare the effectiveness of dexamethasone and magnesium sulfate added as adjuvants to bupivacaine in infraclavicular brachial plexus block used under ultrasound guidance for upper extremity surgeries.
This study was conducted on 90 patients who underwent upper extremity surgery under infraclavicular brachial plexus block. 90 patients included in the study were randomized into 3 groups of 30 people each by the sealed envelope method. 30 participants were included in Group Bupivacaine, 30 participants were included in Group Bupivacaine + Dexamethasone and 30 participants were included in Group Bupivacaine + Magnesium sulfate. The study was started as double blind. According to the local anesthetic used, patients were group B (30 patients, 20 cc 0.5% bupivacaine + 5 cc 0.9% NaCl), group B+D (30 patients, 20 cc 0.5% bupivacaine + 4 mg dexamethasone + 4 cc 0.9% NaCl), group They were divided into three groups as B+M (30 patients, 20 cc 0.5% bupivacaine + 150 mg magnesium sulfate + 4 cc 0.9% NaCl). Complications of the patients, such as sensory block and motor block onset times, peroperative hemodynamic parameters, need for additional analgesia, postoperative block duration, analgesia duration, opioid and NSAID consumption, nausea and vomiting, were recorded
Age
18 - 65 years
Sex
ALL
Healthy Volunteers
Yes
Haci Yusuf GUNES
Van, Turkey (Türkiye)
Start Date
January 2, 2023
Primary Completion Date
January 2, 2023
Completion Date
July 20, 2023
Last Updated
October 17, 2023
90
ACTUAL participants
Bupivacaine + dexamethasone
DRUG
Bupivacaine + magnesium sulphate
DRUG
bupivacaine
DRUG
Lead Sponsor
Yuzuncu Yil University
NCT07432711
NCT06259994
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT06568289