COPD Case Finding In Nottingham and District: C-FIND COPD A Pilot Study

Ever smokers, aged between 55 to 74 years are invited for a telephone risk assessment. Those who are high risk (based on validated lung cancer risk scores, which incorporate a number of variables, including age and smoking intensity) are then sequentially invited for a CT scan in a certain locality of Nottingham as part of the TLHC. As the programme is introduced the number of invites per month will increase from 500 to 1800. It is anticipated that 40 to 45% of those will take up the invite and have a CT scan. At the time of their CT scan all smokers will be offered smoking cessation. The clinical pathway incorporates that the CT scans will be reported by Heart Lung Health , with responsible clinician - Dr O'Dowd. Patients identified as having cancer or high likelihood will be approached and commenced on a cancer diagnostic pathway. This study addresses people who are not entering this pathway. Two-three weeks after the CT scan, the clinical team will invite people to attend for a research study to assess lung health if they have symptoms of cough, breathlessness or 2 or more courses antibiotics in the last 15 months. No further reminder will be sent. The investigators will not excluding people with COPD already and will not turn away high-risk people who self-present even if not had a CT. The invite will include mention of when the mobile unit is open and in their locality, what the visit consists of and that participants are free to come down at a convenient time. A telephone number and e-mail will be provided if somebody contacts the investigators and would prefer to be seen in a standard research unit - an appointment will be provided. The letter will remind participants that this cannot cover broader medical issues or emergencies, where usual clinical advice should be sought. Following informed consent, the following will occur by trained clinical research practitioners and under the support of a research nurse. * Questionnaires: * Symptom scores and information on tobacco smoking / other exposures, past medical history, medication * COPD Assessment Test (CAT) Quality of Life score * Medical Research Council (MRC) breathlessness score * Exacerbation frequency * EQ5D - Health Status * Observations: * Oximetry for heart rate and oxygen saturations * Height * Weight * Blood pressure * Postbronchodilator spirometry - salbutamol delivered by trained staff. * Forced Oscillation Technique (FOT)- a non-clinically used breathing test but might have a role in early detection. * Approach for future research and store research data obtained here / review medical records for future medicines. * Invite to provide a blood sample and nasal swab for early markers of COPD - optional and currently of no clinical relevance. Those with clinical evidence of COPD will be given information by a registered Health Care professional trained to do so on: * COPD and what it is. * Need for immunisations. * General health education, self-management and tobacco cessation where indicated. * Whether further review at the surgery is required. * Clinical information will be fed back to primary care surgery and uploaded onto medical health records, such as SystemOne. The participant will have consented to this. The investigators will seek feedback from participants and subsequently from the primary care clinicians. A qualitative sub-study has been added to assess the opportunities or barriers for people being invited for a COPD diagnosis visit in the community. This sub-study will have a recruitment target of 20 participants. It will involve transcribed interviews. This will help determine the accessibility of the mobile research unit in use for this study.