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Fusion Status After ACDF | Clinical Trials | Clareo Health

UNKNOWNNA

Fusion Status After ACDF

Fusion Status of Machined Allograft Versus Iliac Crest Allograft in Anterior Cervical Discectomy and Fusion: A Randomized Controlled Trial

NCT05986006•Rothman Institute Orthopaedics

View on ClinicalTrials.gov

Summary

Detailed Description

Pseudarthrosis, a failure of bony fusion, is one of the most common causes of revision surgery following anterior cervical discectomy and fusion (ACDF). The interbody spacer is an important component of bony fusion in ACDF, and we aim to compare machined allograft spacers versus iliac crest allograft in a randomized controlled trial. We hypothesize that iliac crest allograft will improve anterior cervical discectomy and fusion arthrodesis rates and diminish the amount of intervertebral graft resorption when compared to off-the-shelf machined allografts

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•patients 18 years of age or older
•preoperative diagnosis of cervical radiculopathy and/or cervical myelopathy.

Exclusion Criteria

•patients undergoing a revision cervical procedure
•current smokers
•patient with surgical indications of tumor, infection, or trauma

Locations (1)

Rothman Orthopaedic Institute

Philadelphia, Pennsylvania, United States

Key Dates

Start Date

August 7, 2023

Primary Completion Date

August 31, 2024

Completion Date

August 31, 2024

Last Updated

August 14, 2023

Enrollment

124

ESTIMATED participants

Conditions

Spine FusionSpine Surgery

Interventions

Anterior Cervical Disc Fusion (ACDF) Surgery w/ machined bone allograft

PROCEDURE

Anterior Cervical Disc Fusion (ACDF) Surgery w/ Iliac Crest Bone Graft

PROCEDURE

MagnetOs Flex Matrix Compared to Trinity Elite Mixed With Local Autograft in Patients Undergoing up to Four-level Instrumented Posterolateral Fusion

NCT05037968

Degenerative Disc DiseaseSpine Fusion+1 more

View study

RECRUITINGNA

An Open, Parallel-group, Randomized, Medical Device Study to Assess the Usability and Performance of Surgify HaloTM in Spine Surgery Versus State-of-art (Rosen Burr)

NCT06827795

Spine Surgery

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: August 14, 2023Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Fusion Status After ACDF

Inclusion Criteria

Exclusion Criteria

MagnetOs Flex Matrix Compared to Trinity Elite Mixed With Local Autograft in Patients Undergoing up to Four-level Instrumented Posterolateral Fusion

An Open, Parallel-group, Randomized, Medical Device Study to Assess the Usability and Performance of Surgify HaloTM in Spine Surgery Versus State-of-art (Rosen Burr)

Lumoptik BRIGHTPOINT Reflectometer Device for Lumbar Epidural Placement

Multifidus Cervicis Plane Block Vs. Sham Block For Posterior Cervical Spine Fusion Surgery

Effect of Ketamine on Intraoperative Motor Evoked Potentials

Irrisept Solution for Instrumented Spine Surgery