Loading clinical trials...

Elimination of Odor and Treatment of Malodorous Recalcitrant Wounds by Using Supraz and PRP-FG Versus Standard of Care | Clinical Trials | Clareo Health

RECRUITINGPHASE2/PHASE3

Elimination of Odor and Treatment of Malodorous Recalcitrant Wounds by Using Supraz and PRP-FG Versus Standard of Care

Repairing Gel (Supraz) and Platelet-rich Plasma-Fibrin Glue (PRP-FG) in Eliminating Odor and Healing the Malodorous Chronic Wounds Versus Standard of Care

NCT05983302•Mashhad University of Medical Sciences

View on ClinicalTrials.gov

Summary

The aim of this study is to eliminate the malodorous of chronic wound and increase the chance of the healing of recalcitrant wounds by using the repairing gel (supraz gel) which has the approved components in wound healing and platelet-rich plasma-fibrin glue.

Detailed Description

The current study assesses the effects of platelet-rich plasma-fibrin glue (PRP-FG) along with the use of the repairing gel which has the approved components on wound healing in patients with chronic wounds and to eliminate the malodorous of chronic wound. This randomized controlled trial is performed on patients with chronic wounds. Patients will be treated with repairing gel (supraz gel) plus PRP-FG dressing (intervention group) or only Supraz gel (intervention group) or only PRP-FG dressing (intervention group) every 48 hours for 8 weeks versus standard of care of treatment (control group: irrigation of wound by normal saline 0.9%).

Eligibility

Age

All ages

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Having a single wound on the body that has been at least 3 months old and has not been repaired by wound irrigation with normal saline and changing the dressing
•Having a body mass index of 18-35
•Sign the informed consent by the patient

Exclusion Criteria

•Having concurrent diseases that may cause problems in wound healing, such as cancers, vasculitis, kidney and liver failure, and heart failure
•Taking certain drugs that may interfere with wound healing, such as corticosteroids, immunosuppressive agents, and cytotoxic agents

Locations (2)

Medical School, Aristotle University of Thessaloniki

Thessaloniki, Greece

Mashhad University of Medical Sciences

Mashhad, Razavi Khorasan Province, Iran

Key Dates

Start Date

August 20, 2023

Primary Completion Date

January 20, 2024

Completion Date

March 20, 2024

Last Updated

March 26, 2024

Enrollment

ESTIMATED participants

Conditions

Wounds and Injuries

Interventions

Platelet-Rich Plasma-Fibrin Glue

DRUG

Repairing Gel

DRUG

Repairing Gel and Platelet-Rich Plasma-Fibrin Glue

DRUG

Classical wound irrigation (control)

OTHER

Contacts

Daryoush Hamidi Alamdari, Ph.D

CONTACT

+98 9151017650 hamidiad@mums.ac.ir

Elaheh Emadi, Ph.D

CONTACT

+98 9355850931 EmadiE4001@mums.ac.ir

4-Aminopyridine to Treat Skin Burns

NCT06596434

BurnsSecond Degree Burn+1 more

View study

RECRUITING

Machine Learning for Handheld Vascular Studies

NCT02932176

AtherosclerosisWounds and Injuries

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 26, 2024Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Elimination of Odor and Treatment of Malodorous Recalcitrant Wounds by Using Supraz and PRP-FG Versus Standard of Care

Inclusion Criteria

Exclusion Criteria

4-Aminopyridine to Treat Skin Burns

Machine Learning for Handheld Vascular Studies

Effects of Advanced Trauma Life Support® on Adult Trauma Patient Outcomes

Artificial Intelligence in Surgical Practice in Sudan: National Survey of Doctors

Non-pharmacological Pain Care During Complex Wound Care Procedures

Study on the Effectiveness of Hypothermal Sulphurous Water in Wound Hygiene