Effect of Staphylococcus and Neisseria Tablets on Clinical Outcome Among Patients With Chronic Obstructive Pulmonary Disease

Exclusion Criteria

• •Patients with active pulmonary tuberculosis, asthma, or uncontrolled advanced malignant tumors; or after partial, lobar, or total pneumonectomy.
• •Patients with acute cardio cerebral vascular disease such as acute myocardial infarction, acute stroke and acute heart failure.
• •Patients with liver failure or renal failure and need blood purification treatment.
• •Patients with rheumatic diseases and autoimmune diseases.
• •Have participated or currently in interventional clinical trials within 30 days.
• •Patients with previous (within 3 months before signing the informed consent) or current use of immunomodulatory drugs (including thymosin, thymosin, interferon, transfer factor, BCG vaccine polysaccharide, and any kind of bacterial extract such as Biostim, pneumonia vaccine, and influenza vaccine).
• •Currently pregnant or breast-feeding women, or those who have fertility but cannot take contraceptive measures during the study period.
• •Other conditions that are not suitable for the trials according to investigator's judgement.