Loading clinical trials...

COMPLETED

Neonatal Electrical Activity at Different Altitude Levels

Neonatal Electrical Activity at Different Altitude Levels: A Prospective Observational Cohort Study

NCT05966714•Children's Hospital of Fudan University

Summary

In this study, the objective is to compare neonatal cerebral electrical activity within 3 days after birth across different altitude areas using amplitude-integrated electroencephalography (aEEG), and establish reference value for each altitude level.

Eligibility

Age

0 - 0 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•1. Singleton term infants (gestational age between 37 0/7 and 41 6/7 weeks) born in the participating hospital.
•2. Infants appear well as defined by normal vital signs (heart rate ranging from 110 to 180 beats/min, respiratory rate ranging from 30 to 60 breaths/min, temperature ranging from 36.5°C to 37.5°C), absence of signs of illness such as cyanosis, respiratory distress and heart murmur.
•3. The mother is permanent residence of the current altitude level and live in the study area for the entire duration of pregnancy.

Exclusion Criteria

•1. Need for supplemental oxygen or assisted ventilation.
•2. Any evidence of intrauterine distress such as meconium-stained amniotic fluid, Apgar score \<7 at 1 or 5 min.
•3. Referred to neonatal intensive care unit or neonatology department for any reason other than observation.
•4. With major congenital anomaly.
•5. Probes cannot be properly placed due to scalp lesions or hematomas.
•6. Reject or withdraw from the study.

Locations (2)

Yangfang Li

Kunming, Yunnan, China

Children Hospital of Fudan University

Shanghai, China

Key Dates

Start Date

June 12, 2023

Primary Completion Date

June 1, 2024

Completion Date

October 8, 2024

Last Updated

February 19, 2025

Enrollment

531

ACTUAL participants

Conditions

Altitude HypoxiaNeonatal Encephalopathy

Interventions

aEEG

DEVICE

Neonatal Neurologic Intensive Care Network of China

NCT02544100

Neonatal EncephalopathySuspected Neonatal Encephalopathy

View study

COMPLETEDNA

Telemedicine to Improve Use of Therapeutic Hypothermia in Rural Settings

NCT03706417

Neonatal Encephalopathy

View study

WITHDRAWNEARLY_PHASE1

Cell-Based Therapy for White Matter Repair in Periventricular Leukomalacia

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 19, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Neonatal Electrical Activity at Different Altitude Levels

Inclusion Criteria

Exclusion Criteria

Neonatal Neurologic Intensive Care Network of China

Telemedicine to Improve Use of Therapeutic Hypothermia in Rural Settings

Cell-Based Therapy for White Matter Repair in Periventricular Leukomalacia

Dexmedetomidine Versus Morphine During Cooling Therapy in Neonates

Telemedicine to Reduce Disparities in the Identification and Treatment of Neonatal Encephalopathy

Effect of Isocaloric Ketogenic Diet on Physical Performance at High Altitude