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Xiyuan Hospital of China Academy of Chinese Medical Sciences
Male infertility affects millions of males worldwide and is rising in prevalence due to social and environmental conditions. Asthenozoospermia (AZS) and oligoasthenozoospermia (OA) are the major causes of male infertility. The diagnosis of male infertility has a negative effect on men's physical and psychological status, poses a threat to their social relationships, lowers self-esteem, and disrupts family harmony. At present, the treatment of ASZ and OA are all mostly empirical, including antioxidants, endocrine therapy, and anti-infection. However, there are still limitations due to inefficiencies. Linggui Yangyuan paste (LGYY), a traditional Chinese compound herbal past, had been used to treat ASZ and OA for several years at the Xiyuan Hospital of China Academy of Chinese Medical Sciences. The investigators designed this program to study the efficacy and safety of LGYY for the treatment of patients with male infertility (AZS and OA).
Age
22 - 45 years
Sex
MALE
Healthy Volunteers
Yes
Start Date
June 1, 2023
Primary Completion Date
June 1, 2024
Completion Date
December 1, 2024
Last Updated
April 27, 2023
162
ESTIMATED participants
LGYY
DRUG
LGYY mimetic
DRUG
WZYZ
DRUG
WZYZ mimetic
DRUG
Lead Sponsor
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Collaborators
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT06921395