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COMPLETEDPhase 4NCT05724511

The Effect of Probiotics on Depression Syndrome and Risk Factors of Cardiovascular Disease in Hemodialysis Patients

As the investigators know, only few researches focus on the effect of probiotics on depression in hemodialysis patients. Besides, probiotics also have benefit effect on dyslipidemia and hypertension i...

Lead sponsor: China Medical University Hospital•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

China Medical University Hospital

Age

20 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Adults aged 20 years or older undergoing hemodialysis (at least 3 months), 3 times per week, and URR ≥65%

Exclusion Criteria

•1. allergic to the components of the intervention drug, low tolerance of milk or dairy products
•2. Has the diagnosis of dementia, delirium, bipolar disorder, schizophrenia, or liver failure
•3. Beck Depression Inventory Chinese version 2.0 score higher than 14, or has significant suicide risk during study
•4. Following significantly clinical syndrome: obsessive compulsive disorder, schizoid personality disorder, schizotypal personality, paranoid、antisocial Personality Disorder, histrionic personality disorder
•5. With addiction to alcohol or drugs, terminal cancer, severe infection, heart failure, central venous catheter in the past 6 months
•6. Taking antibiotics, anti-oxidant vitamin supplement, probiotics, prebiotics, antidepressants, anti-anxiety medicine, yogurt and the products in the past 3 months
•7. Pregnant or lactating

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: September 22, 2023Terms

Trial snapshot

StatusCOMPLETED

PhasePHASE4

Enrollment55

Start dateFeb 2023

Last updatedSep 22, 2023

Condition

Depression Mild Cardiovascular Diseases

Locations shown

China Medical University Hospital

Taichung

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: September 22, 2023Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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