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miRNA and FGF21 Profile in First Trimester and Efficacy of Gestational Diabetes Prediction and Pregnancy Outcomes
The goal of this observational study is to compare miRNA and FGF21 in pregnancy with and without GDM (Gestational Diabetes) The main question it aims to answer that miRNA and FGF21 are different between two groups. Participants will be retrieved blood sample during first trimester and undergone 100 gm OGTT (oral glucose challenge test) during 24-28 weeks of gestation.
Pregnant women who attended antenatal care at Maharaj Nakorn Chiang Mai hospital during first trimester were recruited. Participants received routine standard prenatal care except, 1. additional blood test during 11-13 week 6 days (Blood was collected for further analysis) 2. performed 75gm OGTT during 24-28 week Baseline data and pregnancy outcome were reviewed.
Age
0 - 45 years
Sex
FEMALE
Healthy Volunteers
Yes
Maharaj Nakorn ChiangMai Hospital
Chiang Mai, ChiangMai, Thailand
Start Date
August 26, 2000
Primary Completion Date
November 21, 2022
Completion Date
March 17, 2026
Last Updated
March 18, 2026
160
ACTUAL participants
blood draw
OTHER
Lead Sponsor
Chiang Mai University
NCT06648174
NCT06948825
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