Lead Sponsor

Maria José Clara Colomina Soler

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

•Patients over 65 years of age and/or physical condition ASA III or IV.
•Patients who have major elective abdominal surgery indicated: general surgery, urology, gynecology, by laparoscopic or open approaches.
•Patients who sign the informed consent, agreeing to participate in the study.

•Stage 4 or 5 chronic kidney disease (eGFR \< 15 ml/ min)
•Renal transplantation in the previous 12 months
•Glomerulonephritis, interstitial nephritis or vasculitis
•Anuria at inclusion
•Pre-existing AKI
•Renal replacement therapy (RRT) in the last 90 days
•Indication for renal replacement at the time of inclusion
•Participation in another interventional trial investigating a drug/intervention affecting renal function
•Patients with atrial fibrillation
•Patients with known cardiac shunts.
•Patients whose surgical indication is urgent
•Pregnancy or lactation
•Patients expected to die within 30 days.
•Acute myocardial ischemia within the previous 30 days.
•Acute pulmonary edema within the previous 30 days
•Any contraindication to vasoactive or inotropic medication at low doses

Related studies

NCT07537491 · Colorectal Cancer Postoperative Complications

NCT05360069 · Postoperative Complications, Operative Time, and more

NCT06464978 · Gastric Cancer, Gastrostomy, and more

NCT06430957 · Obstructive Sleep Apnea Risk Management, Postoperative Complications, and more

NCT04725916 · Postoperative Wound Infection, Postoperative Complications, and more

Hypotension Prediction Index-guided Hemodynamic Optimization Trial to Reduce Postoperative Acute Kidney Injury (HYT).