Mandibular Advancement Device and Changes in Nocturia

Exclusion Criteria

• •Patients with concomitant diagnosed sleep disorders (i.e. insomnia, narcolepsy, restless legs syndrome, rapid eye movement sleep behavior disorder).
• •Prostate/kidney problems (urological disease: (eg overactive bladder, benign prostate hyperplasia)
• •Pregnancy
• •Heart failure, use of diuretics, diabetes, Parkinson's disease or dementia.
• •Patients using combination therapy for the management of obstructive sleep apnea (OSA) (i.e. positive airway pressure (PAP) therapy or positional therapy).
• •Upon clinical examination: periodontal disease (\>4 mm on periodontal probing, with bleeding on probing, visual signs of periodontal inflammation); tooth horizontal mobility \>1 mm, vertical mobility, and unfavorable crown to root ratio; open cavities, loose or fractured restorations, or patient undergoing restorative dental treatments.
• •Exaggerated gag reflex.
• •Lack of coordination or dexterity.
• •Inadequate English comprehension.